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Nonetheless, certain critical limitations of MSC-based therapy remain and need to be overcome before widespread clinical application becomes possible [5]

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In many cases, the term drug refers to cytotoxic (chemotherapeutic) anti-cancer agents, but a broad spectrum of therapeutically active moieties can be meant

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Food and Drug Administration rules prohibit advertising of drugs that have not been fully approved by the FDA 21 CFR 314.80: Postmarketing Reporting of Adverse Drug Experiences "MedWatch: The FDA Safety Information and Adverse Event Reporting Program"